Cargando…

The NO/cGMP/PKG pathway in platelets: The therapeutic potential of PDE5 inhibitors in platelet disorders

Platelets are the “guardians” of the blood circulatory system. At sites of vessel injury, they ensure hemostasis and promote immunity and vessel repair. However, their uncontrolled activation is one of the main drivers of thrombosis. To keep circulating platelets in a quiescent state, the endotheliu...

Descripción completa

Detalles Bibliográficos
Autores principales: Degjoni, Anisa, Campolo, Federica, Stefanini, Lucia, Venneri, Mary Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805178/
https://www.ncbi.nlm.nih.gov/pubmed/35950928
http://dx.doi.org/10.1111/jth.15844