Asymmetric Alkylation of Cyclic Ketones with Dehydroalanine via H‐Bond‐Directing Enamine Catalysis: Straightforward Access to Enantiopure Unnatural α‐Amino Acids

The growing importance of structurally diverse and functionalized enantiomerically pure unnatural amino acids in the design of drugs, including peptides, has stimulated the development of new synthetic methods. This study reports the challenging direct asymmetric alkylation of cyclic ketones with de...

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Detalles Bibliográficos
Autores principales: Retini, Michele, Bartolucci, Silvia, Bartoccini, Francesca, Piersanti, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805190/
https://www.ncbi.nlm.nih.gov/pubmed/35916657
http://dx.doi.org/10.1002/chem.202201994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805190/
https://www.ncbi.nlm.nih.gov/pubmed/35916657
http://dx.doi.org/10.1002/chem.202201994

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