Antigen-presenting T cells provide critical B7 co-stimulation for thymic iNKT cell development via CD28-dependent trogocytosis

Invariant natural killer T (iNKT) cell development in the thymus depends on T cell receptor recognition of CD1d ligand on CD4/CD8 double-positive thymocytes. We previously reported that B7-CD28 co-stimulation is required for thymic iNKT cell development, but the cellular and molecular mechanisms und...

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Detalles Bibliográficos
Autores principales: Watanabe, Masashi, Celli, Sofia, Alkhaleel, Farrah A., Hodes, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805342/
https://www.ncbi.nlm.nih.gov/pubmed/36450247
http://dx.doi.org/10.1016/j.celrep.2022.111731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805342/
https://www.ncbi.nlm.nih.gov/pubmed/36450247
http://dx.doi.org/10.1016/j.celrep.2022.111731

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