VX-765 Alleviates β-Amyloid Deposition and Secondary Degeneration in the Ipsilateral Hippocampus and Ameliorates Cognitive Decline after Focal Cortical Infarction in Rats

Focal cortical infarction leads to secondary degeneration of the ipsilateral hippocampus, which is associated with poststroke cognitive impairment. VX-765 is a potent small-molecule caspase-1 inhibitor that protects against central nervous system diseases. The present study aimed to determine the pr...

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Detalles Bibliográficos
Autores principales: Dong, Dawei, Ren, Aihui, Yang, Ying, Su, Jiayi, Liu, Libin, Zhuo, Wenyan, Liang, Yubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805416/
https://www.ncbi.nlm.nih.gov/pubmed/36441377
http://dx.doi.org/10.1007/s12031-022-02088-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805416/
https://www.ncbi.nlm.nih.gov/pubmed/36441377
http://dx.doi.org/10.1007/s12031-022-02088-6

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