Chromatin remodeler CHD7 targets active enhancer region to regulate cell type-specific gene expression in human neural crest cells

A mutation in the chromatin remodeler chromodomain helicase DNA-binding 7 (CHD7) gene causes the multiple congenital anomaly CHARGE syndrome. The craniofacial anomalies observed in CHARGE syndrome are caused by dysfunctions of neural crest cells (NCCs), which originate from the neural tube. However,...

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Detalles Bibliográficos
Autores principales: Sanosaka, Tsukasa, Okuno, Hironobu, Mizota, Noriko, Andoh-Noda, Tomoko, Sato, Miki, Tomooka, Ryo, Banno, Satoe, Kohyama, Jun, Okano, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805427/
https://www.ncbi.nlm.nih.gov/pubmed/36587182
http://dx.doi.org/10.1038/s41598-022-27293-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805427/
https://www.ncbi.nlm.nih.gov/pubmed/36587182
http://dx.doi.org/10.1038/s41598-022-27293-6

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