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Syllable-PBWT for space-efficient haplotype long-match query

MOTIVATION: The positional Burrows–Wheeler transform (PBWT) has led to tremendous strides in haplotype matching on biobank-scale data. For genetic genealogical search, PBWT-based methods have optimized the asymptotic runtime of finding long matches between a query haplotype and a predefined panel of...

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Detalles Bibliográficos
Autores principales: Wang, Victor, Naseri, Ardalan, Zhang, Shaojie, Zhi, Degui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805553/
https://www.ncbi.nlm.nih.gov/pubmed/36440908
http://dx.doi.org/10.1093/bioinformatics/btac734