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AlphaPulldown—a python package for protein–protein interaction screens using AlphaFold-Multimer

SUMMARY: The artificial intelligence-based structure prediction program AlphaFold-Multimer enabled structural modelling of protein complexes with unprecedented accuracy. Increasingly, AlphaFold-Multimer is also used to discover new protein–protein interactions (PPIs). Here, we present AlphaPulldown,...

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Detalles Bibliográficos
Autores principales: Yu, Dingquan, Chojnowski, Grzegorz, Rosenthal, Maria, Kosinski, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805587/
https://www.ncbi.nlm.nih.gov/pubmed/36413069
http://dx.doi.org/10.1093/bioinformatics/btac749