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The mitochondrial UPR regulator ATF5 promotes intestinal barrier function via control of the satiety response

Organisms use several strategies to mitigate mitochondrial stress, including the activation of the mitochondrial unfolded protein response (UPR(mt)). The UPR(mt) in Caenorhabditis elegans, regulated by the transcription factor ATFS-1, expands on this recovery program by inducing an antimicrobial res...

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Detalles Bibliográficos
Autores principales: Chamseddine, Douja, Mahmud, Siraje A., Westfall, Aundrea K., Castoe, Todd A., Berg, Rance E., Pellegrino, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805788/
https://www.ncbi.nlm.nih.gov/pubmed/36516750
http://dx.doi.org/10.1016/j.celrep.2022.111789