LC-MS/MS method for the quantitation of serum tocilizumab in rheumatoid arthritis patients using rapid tryptic digestion without IgG purification

The quantitation of serum tocilizumab using liquid chromatography tandem-mass spectrometry (LC-MS/MS) method has not been widely applied in clinical settings because of its time-consuming and costly sample pretreatments. The present study aimed to develop a validated LC-MS/MS method for detecting se...

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Detalles Bibliográficos
Autores principales: Mochizuki, Takashi, Shibata, Kaito, Naito, Takafumi, Shimoyama, Kumiko, Ogawa, Noriyoshi, Maekawa, Masato, Kawakami, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805942/
https://www.ncbi.nlm.nih.gov/pubmed/36605577
http://dx.doi.org/10.1016/j.jpha.2022.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805942/
https://www.ncbi.nlm.nih.gov/pubmed/36605577
http://dx.doi.org/10.1016/j.jpha.2022.08.003

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