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Peptide-RNA complexation-induced fluorescence “turn on” displacement assay for the recognition of small ligands targeting HIV-1 RNA
The regulator of expression of virion (Rev) protein binds specifically to the Rev-responsive element (RRE) RNA in order to regulate the expression of the human immunodeficiency virus (HIV)-1 genes. Fluorescence indicator displacement assays have been used to identify ligands that can inhibit the Rev...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805967/ https://www.ncbi.nlm.nih.gov/pubmed/36605574 http://dx.doi.org/10.1016/j.jpha.2022.07.003 |