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Peptide-RNA complexation-induced fluorescence “turn on” displacement assay for the recognition of small ligands targeting HIV-1 RNA

The regulator of expression of virion (Rev) protein binds specifically to the Rev-responsive element (RRE) RNA in order to regulate the expression of the human immunodeficiency virus (HIV)-1 genes. Fluorescence indicator displacement assays have been used to identify ligands that can inhibit the Rev...

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Detalles Bibliográficos
Autores principales: Qi, Liang, Zhang, Jiayun, Gao, Ying, Gong, Pin, Liang, Chengyuan, Su, Yao, Zeng, Qiao, Zhang, Yafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805967/
https://www.ncbi.nlm.nih.gov/pubmed/36605574
http://dx.doi.org/10.1016/j.jpha.2022.07.003