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Multiplex immunofluorescence and single‐cell transcriptomic profiling reveal the spatial cell interaction networks in the non‐small cell lung cancer microenvironment

BACKGROUND: Conventional immunohistochemistry technologies were limited by the inability to simultaneously detect multiple markers and the lack of identifying spatial relationships among cells, hindering understanding of the biological processes in cancer immunology. METHODS: Tissue slices of primar...

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Detalles Bibliográficos
Autores principales: Peng, Haoxin, Wu, Xiangrong, Liu, Shaopeng, He, Miao, Xie, Chao, Zhong, Ran, Liu, Jun, Tang, Chenshuo, Li, Caichen, Xiong, Shan, Zheng, Hongbo, He, Jianxing, Lu, Xu, Liang, Wenhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806015/
https://www.ncbi.nlm.nih.gov/pubmed/36588094
http://dx.doi.org/10.1002/ctm2.1155