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Reversal of splicing infidelity is a pre-activation step in B cell differentiation

INTRODUCTION: B cell activation and differentiation is central to the adaptive immune response. Changes in exon usage can have major impacts on cellular signaling and differentiation but have not been systematically explored in differentiating B cells. METHODS: We analyzed exon usage and intron rete...

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Detalles Bibliográficos
Autores principales: O’Grady, Tina M., Baddoo, Melody, Flemington, Samuel A., Ishaq, Eman Y., Ungerleider, Nathan A., Flemington, Erik K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806119/
https://www.ncbi.nlm.nih.gov/pubmed/36601126
http://dx.doi.org/10.3389/fimmu.2022.1060114