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Longitudinal in vivo biodistribution of nano and micro sized hydroxyapatite particles implanted in a bone defect
Hydroxyapatite (HA) has been widely used as a bone substitute and more recently as a carrier for local delivery of bone targeted drugs. Majority of the approved HA based biomaterials and drug carriers comprise of micrometer sized particulate HA (mHA) or granules and can therefore only be used for ex...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806272/ https://www.ncbi.nlm.nih.gov/pubmed/36601389 http://dx.doi.org/10.3389/fbioe.2022.1076320 |