Endogenous Bok is stable at the endoplasmic reticulum membrane and does not mediate proteasome inhibitor-induced apoptosis

Controversy surrounds the cellular role of the Bcl-2 family protein Bok. On one hand, it has been shown that all endogenous Bok is bound to inositol 1,4,5-trisphosphate receptors (IP(3)Rs), while other data suggest that Bok can act as a pro-apoptotic mitochondrial outer membrane permeabilization med...

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Detalles Bibliográficos
Autores principales: Bonzerato, Caden G., Keller, Katherine R., Schulman, Jacqualyn J., Gao, Xiaokong, Szczesniak, Laura M., Wojcikiewicz, Richard J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806350/
https://www.ncbi.nlm.nih.gov/pubmed/36601536
http://dx.doi.org/10.3389/fcell.2022.1094302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806350/
https://www.ncbi.nlm.nih.gov/pubmed/36601536
http://dx.doi.org/10.3389/fcell.2022.1094302

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