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Endogenous Bok is stable at the endoplasmic reticulum membrane and does not mediate proteasome inhibitor-induced apoptosis
Controversy surrounds the cellular role of the Bcl-2 family protein Bok. On one hand, it has been shown that all endogenous Bok is bound to inositol 1,4,5-trisphosphate receptors (IP(3)Rs), while other data suggest that Bok can act as a pro-apoptotic mitochondrial outer membrane permeabilization med...
Autores principales: | Bonzerato, Caden G., Keller, Katherine R., Schulman, Jacqualyn J., Gao, Xiaokong, Szczesniak, Laura M., Wojcikiewicz, Richard J. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806350/ https://www.ncbi.nlm.nih.gov/pubmed/36601536 http://dx.doi.org/10.3389/fcell.2022.1094302 |
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