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Microsecond-long simulation reveals the molecular mechanism for the dual inhibition of falcipain-2 and falcipain-3 by antimalarial lead compounds

The latest world malaria report revealed that human deaths caused by malaria are currently on the rise and presently stood at over 627,000 per year. In addition, more than 240 million people have the infection at any given time. These figures make malaria the topmost infectious disease and reiterate...

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Detalles Bibliográficos
Autores principales: Danazumi, Ammar Usman, Balogun, Emmanuel Oluwadare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806354/
https://www.ncbi.nlm.nih.gov/pubmed/36601587
http://dx.doi.org/10.3389/fmolb.2022.1070080