Neutropenia in Cynomolgus Monkeys With Anti-Drug Antibodies Associated With Administration of Afucosylated Humanized Monoclonal Antibodies

Removal of the core fucose from the Fc region of humanized monoclonal antibodies (afucosylated antibodies) enhances their antibody-dependent cell cytotoxicity activities in killing cancer cells. Based on the authors’ experience and literature, administrations of afucosylated antibodies have been ass...

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Detalles Bibliográficos
Autores principales: Adedeji, Adeyemi O., Zhong, Fiona, Getz, Jennifer A., Zhong, Zoe, Halpern, Wendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806483/
https://www.ncbi.nlm.nih.gov/pubmed/36329562
http://dx.doi.org/10.1177/01926233221131510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806483/
https://www.ncbi.nlm.nih.gov/pubmed/36329562
http://dx.doi.org/10.1177/01926233221131510

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