GBA inhibition suppresses ovarian cancer growth, survival and receptor tyrosine kinase AXL-mediated signaling pathways

The poor outcome of advanced ovarian cancer under conventional therapy necessitates new strategies to improve therapeutic efficacy. β-glucosidase (encoded by GBA) is a lysosomal enzyme and is involved in sphingolipids metabolism. Recent studies revealed that β-glucosidase plays a role in cancer deve...

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Detalles Bibliográficos
Autores principales: Wang, Gang, Ouyang, Baisha, Jing, Fang, Dai, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806639/
https://www.ncbi.nlm.nih.gov/pubmed/36575930
http://dx.doi.org/10.4196/kjpp.2023.27.1.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806639/
https://www.ncbi.nlm.nih.gov/pubmed/36575930
http://dx.doi.org/10.4196/kjpp.2023.27.1.21

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