Hydrogen sulfide alleviates hypothyroidism-induced myocardial fibrosis in rats through stimulating autophagy and inhibiting TGF-β1/Smad2 pathway

Hypothyroidism alone can lead to myocardial fibrosis and result in heart failure, but traditional hormone replacement therapy does not improve the fibrotic situation. Hydrogen sulfide (H(2)S), a new gas signaling molecule, possesses anti-inflammatory, antioxidant, and anti-fibrotic capabilities. Whe...

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Detalles Bibliográficos
Autores principales: Song, Xiong, Nie, Liangui, Long, Junrong, Zhao, Junxiong, Liu, Xing, Wang, Liuyang, Liu, Da, Wang, Sen, Liu, Shengquan, Yang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806643/
https://www.ncbi.nlm.nih.gov/pubmed/36575928
http://dx.doi.org/10.4196/kjpp.2023.27.1.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806643/
https://www.ncbi.nlm.nih.gov/pubmed/36575928
http://dx.doi.org/10.4196/kjpp.2023.27.1.1

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