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Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ

This study aimed to observe the protective effect of momordicine I, a triterpenoid compound extracted from momordica charantia L., on isoproterenol (ISO)-induced hypertrophy in rat H9c2 cardiomyocytes and investigate its potential mechanism. Treatment with 10 μM ISO induced cardiomyocyte hypertrophy...

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Detalles Bibliográficos
Autores principales: Li, Hongming, Qiu, Yumei, Xie, Mengdie, Ouyang, Changsheng, Ding, Xiaoyun, Zhang, Hao, Dong, Wei, Xiong, Yinhua, Tang, Xilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806645/
https://www.ncbi.nlm.nih.gov/pubmed/36575935
http://dx.doi.org/10.4196/kjpp.2023.27.1.75