Suppression of Selective Voltage-Gated Calcium Channels Alleviates Neuronal Degeneration and Dysfunction through Glutathione S-Transferase-Mediated Oxidative Stress Resistance in a Caenorhabditis elegans Model of Alzheimer's Disease

Calcium homeostasis plays a vital role in protecting against Alzheimer's disease (AD). In this study, amyloid-β (Aβ)-induced C. elegans models of AD were used to elucidate the mechanisms underlying calcium homeostasis in AD. Calcium acetate increased the intracellular calcium content, exacerbat...

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Detalles Bibliográficos
Autores principales: Zheng, Zihui, Wu, Kanglu, Ruan, Qinli, Li, Dongfang, Liu, Weizhen, Wang, Min, Li, Yaoyao, Xia, Jintao, Yang, Dongqing, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806690/
https://www.ncbi.nlm.nih.gov/pubmed/36600949
http://dx.doi.org/10.1155/2022/8287633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806690/
https://www.ncbi.nlm.nih.gov/pubmed/36600949
http://dx.doi.org/10.1155/2022/8287633

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