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Targeted protein degradation by Trim-Away using cell resealing coupled with microscopic image-based quantitative analysis
“Trim-Away” technology enables rapid degradation of endogenous proteins without prior modification of protein-coding genes or mRNAs through delivery of antibodies that target proteins of interest. Although this approach can be readily applied to almost any cytosolic protein, strategies for cytosolic...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806799/ https://www.ncbi.nlm.nih.gov/pubmed/36601537 http://dx.doi.org/10.3389/fcell.2022.1027043 |