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Proton Transfers to DNA in Native Electrospray Ionization Mass Spectrometry: A Quantum Mechanics/Molecular Mechanics Study

[Image: see text] Native electrospray ionization-ion mobility mass spectrometry (N-ESI/IM-MS) is a powerful approach for low-resolution structural studies of DNAs in the free state and in complex with ligands. Solvent vaporization is coupled with proton transfers from ammonium ions to the DNA, resul...

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Detalles Bibliográficos
Autores principales: Paulikat, Mirko, Aranda, Juan, Ippoliti, Emiliano, Orozco, Modesto, Carloni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806827/
https://www.ncbi.nlm.nih.gov/pubmed/36540944
http://dx.doi.org/10.1021/acs.jpclett.2c03100