Functionalized Tetrazoles as Latent Active Esters in the Synthesis of Amide Bonds

[Image: see text] We report the use of N-2,4-dinitrophenyltetrazoles as latent active esters (LAEs) in the synthesis of amide bonds. Activating the tetrazole generates an HOBt-type active ester without the requirement for exogenous coupling agents. The methodology was widely applicable to a range of...

Descripción completa

Detalles Bibliográficos
Autores principales: Elwood, Jessica M. L., Henry, Martyn C., Lopez-Fernandez, J. Daniel, Mowat, Jenna M., Boyle, Mhairi, Buist, Benjamin, Livingstone, Keith, Jamieson, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806851/
https://www.ncbi.nlm.nih.gov/pubmed/36524745
http://dx.doi.org/10.1021/acs.orglett.2c03971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806851/
https://www.ncbi.nlm.nih.gov/pubmed/36524745
http://dx.doi.org/10.1021/acs.orglett.2c03971

Ejemplares similares