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Functionalized Tetrazoles as Latent Active Esters in the Synthesis of Amide Bonds

[Image: see text] We report the use of N-2,4-dinitrophenyltetrazoles as latent active esters (LAEs) in the synthesis of amide bonds. Activating the tetrazole generates an HOBt-type active ester without the requirement for exogenous coupling agents. The methodology was widely applicable to a range of...

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Detalles Bibliográficos
Autores principales:	Elwood, Jessica M. L., Henry, Martyn C., Lopez-Fernandez, J. Daniel, Mowat, Jenna M., Boyle, Mhairi, Buist, Benjamin, Livingstone, Keith, Jamieson, Craig
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806851/ https://www.ncbi.nlm.nih.gov/pubmed/36524745 http://dx.doi.org/10.1021/acs.orglett.2c03971

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