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GPR84 potently inhibits osteoclastogenesis and alleviates osteolysis in bone metastasis of colorectal cancer

The expression of GPR84 in bone marrow-derived monocytes/macrophages (BMMs) can inhibit osteoclast formation; however, its role in bone metastasis of colorectal cancer (CRC) is still unknown. To investigate the effects of GPR84 on bone metastasis of CRC, the murine CRC cell line MC-38 was injected i...

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Detalles Bibliográficos
Autores principales: Jian, Li, Shi-wei, Long, Dan, Jing, Juan, Wu, Wei, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806886/
https://www.ncbi.nlm.nih.gov/pubmed/36593458
http://dx.doi.org/10.1186/s13018-022-03473-y