PCSK9 facilitates melanoma pathogenesis via a network regulating tumor immunity

BACKGROUND: PCSK9 regulates cholesterol homeostasis and promotes tumorigenesis. However, the relevance of these two actions and the mechanisms underlying PCSK9’s oncogenic roles in melanoma and other cancers remain unclear. METHODS: PCSK9’s association with melanoma was analysed using the TCGA datas...

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Detalles Bibliográficos
Autores principales: Gu, Yan, Lin, Xiaozeng, Dong, Ying, Wood, Geoffrey, Seidah, Nabil G., Werstuck, Geoff, Major, Pierre, Bonert, Michael, Kapoor, Anil, Tang, Damu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806914/
https://www.ncbi.nlm.nih.gov/pubmed/36588164
http://dx.doi.org/10.1186/s13046-022-02584-y