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PCSK9 facilitates melanoma pathogenesis via a network regulating tumor immunity
BACKGROUND: PCSK9 regulates cholesterol homeostasis and promotes tumorigenesis. However, the relevance of these two actions and the mechanisms underlying PCSK9’s oncogenic roles in melanoma and other cancers remain unclear. METHODS: PCSK9’s association with melanoma was analysed using the TCGA datas...
Autores principales: | Gu, Yan, Lin, Xiaozeng, Dong, Ying, Wood, Geoffrey, Seidah, Nabil G., Werstuck, Geoff, Major, Pierre, Bonert, Michael, Kapoor, Anil, Tang, Damu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806914/ https://www.ncbi.nlm.nih.gov/pubmed/36588164 http://dx.doi.org/10.1186/s13046-022-02584-y |
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