Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats

Chronic hyperammonemia, a main contributor to hepatic encephalopathy (HE), leads to neuroinflammation which alters neurotransmission leading to cognitive impairment. There are no specific treatments for the neurological alterations in HE. Extracellular vesicles (EVs) from mesenchymal stem cells (MSC...

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Detalles Bibliográficos
Autores principales: Izquierdo-Altarejos, Paula, Cabrera-Pastor, Andrea, Martínez-García, Mar, Sánchez-Huertas, Carlos, Hernández, Alberto, Moreno-Manzano, Victoria, Felipo, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806918/
https://www.ncbi.nlm.nih.gov/pubmed/36593485
http://dx.doi.org/10.1186/s12974-022-02688-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806918/
https://www.ncbi.nlm.nih.gov/pubmed/36593485
http://dx.doi.org/10.1186/s12974-022-02688-4

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