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Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats
Chronic hyperammonemia, a main contributor to hepatic encephalopathy (HE), leads to neuroinflammation which alters neurotransmission leading to cognitive impairment. There are no specific treatments for the neurological alterations in HE. Extracellular vesicles (EVs) from mesenchymal stem cells (MSC...
Autores principales: | Izquierdo-Altarejos, Paula, Cabrera-Pastor, Andrea, Martínez-García, Mar, Sánchez-Huertas, Carlos, Hernández, Alberto, Moreno-Manzano, Victoria, Felipo, Vicente |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806918/ https://www.ncbi.nlm.nih.gov/pubmed/36593485 http://dx.doi.org/10.1186/s12974-022-02688-4 |
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