Biotransformation of hydroxychloroquine to evaluate the cytotoxicity of its metabolites and mimic mammalian metabolism

Hydroxychloroquine (HCQ) displays attractive anti-inflammatory and antiviral effects. Because of that, such a drug made part of some clinical trials for combating Sars-CoV-2 during the COVID-19 pandemic. The present study aimed to conduct the biotransformation of HCQ by filamentous fungi reported as...

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Detalles Bibliográficos
Autores principales: dos Santos, Valmore Henrique Pereira, dos Santos, Wanderleya Toledo, Ionta, Marisa, de Paula, Ana Cláudia Chagas, Silva, Eliane de Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806929/
https://www.ncbi.nlm.nih.gov/pubmed/36619209
http://dx.doi.org/10.1016/j.rechem.2022.100761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806929/
https://www.ncbi.nlm.nih.gov/pubmed/36619209
http://dx.doi.org/10.1016/j.rechem.2022.100761

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