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Differentiable Learning of Sequence-Specific Minimizer Schemes with DeepMinimizer

Minimizers are widely used to sample representative k-mers from biological sequences in many applications, such as read mapping and taxonomy prediction. In most scenarios, having the minimizer scheme select as few k-mer positions as possible (i.e., having a low density) is desirable to reduce comput...

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Detalles Bibliográficos
Autores principales: Hoang, Minh, Zheng, Hongyu, Kingsford, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807081/
https://www.ncbi.nlm.nih.gov/pubmed/36095142
http://dx.doi.org/10.1089/cmb.2022.0275