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Differentiable Learning of Sequence-Specific Minimizer Schemes with DeepMinimizer
Minimizers are widely used to sample representative k-mers from biological sequences in many applications, such as read mapping and taxonomy prediction. In most scenarios, having the minimizer scheme select as few k-mer positions as possible (i.e., having a low density) is desirable to reduce comput...
Autores principales: | Hoang, Minh, Zheng, Hongyu, Kingsford, Carl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807081/ https://www.ncbi.nlm.nih.gov/pubmed/36095142 http://dx.doi.org/10.1089/cmb.2022.0275 |
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