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Angiotensin-(1–7) ameliorates sepsis-induced cardiomyopathy by alleviating inflammatory response and mitochondrial damage through the NF-κB and MAPK pathways

BACKGROUND: There is no available viable treatment for Sepsis-Induced Cardiomyopathy (SIC), a common sepsis complication with a higher fatality risk. The septic patients showed an abnormal activation of the renin angiotensin (Ang) aldosterone system (RAAS). However, it is not known how the Ang II an...

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Detalles Bibliográficos
Autores principales: Chen, Xin-Sen, Cui, Jing-Rui, Meng, Xiang-Long, Wang, Shu-Hang, Wei, Wei, Gao, Yu-Lei, Shou, Song-Tao, Liu, Yan-Cun, Chai, Yan-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807106/
https://www.ncbi.nlm.nih.gov/pubmed/36593471
http://dx.doi.org/10.1186/s12967-022-03842-5