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Angiotensin-(1–7) ameliorates sepsis-induced cardiomyopathy by alleviating inflammatory response and mitochondrial damage through the NF-κB and MAPK pathways
BACKGROUND: There is no available viable treatment for Sepsis-Induced Cardiomyopathy (SIC), a common sepsis complication with a higher fatality risk. The septic patients showed an abnormal activation of the renin angiotensin (Ang) aldosterone system (RAAS). However, it is not known how the Ang II an...
Autores principales: | Chen, Xin-Sen, Cui, Jing-Rui, Meng, Xiang-Long, Wang, Shu-Hang, Wei, Wei, Gao, Yu-Lei, Shou, Song-Tao, Liu, Yan-Cun, Chai, Yan-Fen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807106/ https://www.ncbi.nlm.nih.gov/pubmed/36593471 http://dx.doi.org/10.1186/s12967-022-03842-5 |
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