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Diabetes mellitus impacts on expression of DNA mismatch repair protein PMS2 and tumor microenvironment in pancreatic ductal adenocarcinoma

AIMS/INTRODUCTION: The mismatch repair (MMR) protein recognizes DNA replication errors and plays an important role in tumorigenesis, including pancreatic ductal adenocarcinoma (PDAC). Although PMS2, a MMR protein, is degraded under oxidative stress, the effects of diabetes are still unclear. Herein,...

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Detalles Bibliográficos
Autores principales: Pan, Xuekai, Mizukami, Hiroki, Hara, Yutaro, Yamada, Takahiro, Yamazaki, Keisuke, Kudoh, Kazuhiro, Takeuchi, Yuki, Sasaki, Takanori, Kushibiki, Hanae, Igawa, Akiko, Hakamada, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807152/
https://www.ncbi.nlm.nih.gov/pubmed/36453157
http://dx.doi.org/10.1111/jdi.13929