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Type I Interferon Signaling Is Critical During the Innate Immune Response to HSV-1 Retinal Infection

PURPOSE: Acute retinal necrosis (ARN) is a herpesvirus infection of the retina with blinding complications. In this study, we sought to create a reproducible mouse model of ARN that mimics human disease to better understand innate immunity within the retina during virus infection. METHODS: C57Bl/6J...

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Detalles Bibliográficos
Autores principales: Fan, Shan, Yoo, Jae Hyuk, Park, Garam, Yeh, Steven, Conrady, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807183/
https://www.ncbi.nlm.nih.gov/pubmed/36583876
http://dx.doi.org/10.1167/iovs.63.13.28