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Two cases of CRPC with BRCA mutation treated by olaparib after favorable response to cisplatin

INTRODUCTION: Several prostate cancers carry homologous recombination repair mutations that respond to olaparib. Because of the mechanism, the efficacy of platinum‐based therapy can be used to predict the efficacy of poly(adenosine diphosphate‐ribose) polymerase inhibitors such as olaparib. CASE PRE...

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Detalles Bibliográficos
Autores principales: Miyazawa, Yoshiyuki, Shimizu, Takanori, Sekine, Yoshitaka, Arai, Seiji, Ohtsu, Akira, Fujizuka, Yuji, Nomura, Masashi, Koike, Hidekazu, Matsui, Hiroshi, Suzuki, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807333/
https://www.ncbi.nlm.nih.gov/pubmed/36605692
http://dx.doi.org/10.1002/iju5.12543