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Cathepsin L inhibition prevents the cleavage of multiple nuclear proteins upon lysis of quiescent human cells
Several studies have indicated a role for cathepsin L (CTSL) proteolytic activity in the nucleus under distinct cellular conditions, including during differentiation, senescence, and quiescence. Here we show that addition of CTSL inhibitors to a cell lysis buffer prevents the cleavage of several nuc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Caltech Library
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807461/ https://www.ncbi.nlm.nih.gov/pubmed/36606083 http://dx.doi.org/10.17912/micropub.biology.000716 |