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Combination therapy of lymphatic drug delivery and total body irradiation in a metastatic lymph node and lung mouse model

Chemotherapy using a lymphatic drug delivery system (LDDS) targeting lymph nodes (LNs) in the early stage of metastasis has a superior antitumor effect to systemic chemotherapy. An LDDS produces a higher drug retention rate and tissue selectivity in LNs. To expand the therapeutic coverage of LDDS fr...

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Detalles Bibliográficos
Autores principales: Sora, Shota, Sukhbaatar, Ariunbuyan, Fukushige, Shinichi, Mori, Shiro, Sakamoto, Maya, Kodama, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807513/
https://www.ncbi.nlm.nih.gov/pubmed/36056924
http://dx.doi.org/10.1111/cas.15562