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Drug formulation augments the therapeutic response of carboplatin administered through a lymphatic drug delivery system

Treatment of metastatic lymph nodes (LNs) is challenging due to their unique architecture and biophysical traits. Systemic chemotherapy fails to impede tumor progression in LNs due to poor drug uptake and retention by LNs, resulting in fatal systemic metastasis. To effectively treat LN metastasis, a...

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Detalles Bibliográficos
Autores principales: Mishra, Radhika, Sukhbaatar, Ariunbuyan, Dorai, Arunkumar, Mori, Shiro, Shiga, Kiyoto, Kodama, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807524/
https://www.ncbi.nlm.nih.gov/pubmed/36168838
http://dx.doi.org/10.1111/cas.15599