Effects of Aficamten on cardiac contractility in a feline translational model of hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is the most prevalent inherited cardiac disease in humans and cats and lacks efficacious pharmacologic interventions in the preclinical phase of disease. LV outflow tract obstruction (LVOTO) is commonly observed in HCM-affected patients and is a primary driver of he...

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Detalles Bibliográficos
Autores principales: Sharpe, Ashley N., Oldach, Maureen S., Rivas, Victor N., Kaplan, Joanna L., Walker, Ashley L., Kovacs, Samantha L., Hwee, Darren T., Cremin, Peadar, Morgan, Bradley P., Malik, Fady I., Harris, Samantha P., Stern, Joshua A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807554/
https://www.ncbi.nlm.nih.gov/pubmed/36593243
http://dx.doi.org/10.1038/s41598-022-26630-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807554/
https://www.ncbi.nlm.nih.gov/pubmed/36593243
http://dx.doi.org/10.1038/s41598-022-26630-z

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