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Transcriptional regulation of Notch1 by nuclear factor-κB during T cell activation

Notch1 plays important roles in T cell development and is highly expressed in activated CD4(+) T cells. However, the underlying mechanism of Notch1 transcription in T cells has not been fully characterized. Therefore, we aimed to determine how Notch1 expression is regulated during the activation of...

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Detalles Bibliográficos
Autores principales: Hwang, Jeong-Ryul, Kim, Donghwan, Kang, Jung-Ah, Park, Sang-Heon, Park, Sung-Gyoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807580/
https://www.ncbi.nlm.nih.gov/pubmed/36593298
http://dx.doi.org/10.1038/s41598-022-26674-1