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New thioxothiazolidinyl-acetamides derivatives as potent urease inhibitors: design, synthesis, in vitro inhibition, and molecular dynamic simulation

To identify potent urease inhibitors, in the current study, a series of thioxothiazolidinyl-acetamides were designed and synthesized. The prepared compounds were characterized by spectroscopic techniques, including FTIR, (1)HNMR, (13)CNMR, and elemental analysis. In the enzymatic assessments, it was...

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Detalles Bibliográficos
Autores principales: Dastyafteh, Navid, Noori, Milad, Nazari Montazer, Mohammad, Zomorodian, Kamiar, Yazdanpanah, Somayeh, Iraji, Aida, Khalili Ghomi, Minoo, Javanshir, Shahrzad, Asadi, Mehdi, Dianatpour, Mehdi, Biglar, Mahmood, Larijani, Bagher, Amanlou, Massoud, Mahdavi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807592/
https://www.ncbi.nlm.nih.gov/pubmed/36593349
http://dx.doi.org/10.1038/s41598-022-27234-3