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Combination of the parent analogue of remdesivir (GS-441524) and molnupiravir results in a markedly potent antiviral effect in SARS-CoV-2 infected Syrian hamsters

Remdesivir was the first antiviral drug to be approved for the treatment of severe COVID-19; followed by molnupiravir (another prodrug of a nucleoside analogue) and the protease inhibitor nirmatrelvir. Combination of antiviral drugs may result in improved potency and help to avoid or delay the devel...

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Detalles Bibliográficos
Autores principales: Abdelnabi, Rana, Maes, Piet, de Jonghe, Steven, Weynand, Birgit, Neyts, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807602/
https://www.ncbi.nlm.nih.gov/pubmed/36605401
http://dx.doi.org/10.3389/fphar.2022.1072202