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Combination of the parent analogue of remdesivir (GS-441524) and molnupiravir results in a markedly potent antiviral effect in SARS-CoV-2 infected Syrian hamsters
Remdesivir was the first antiviral drug to be approved for the treatment of severe COVID-19; followed by molnupiravir (another prodrug of a nucleoside analogue) and the protease inhibitor nirmatrelvir. Combination of antiviral drugs may result in improved potency and help to avoid or delay the devel...
Autores principales: | Abdelnabi, Rana, Maes, Piet, de Jonghe, Steven, Weynand, Birgit, Neyts, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807602/ https://www.ncbi.nlm.nih.gov/pubmed/36605401 http://dx.doi.org/10.3389/fphar.2022.1072202 |
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