Functional dissection of N-terminal nuclear trafficking signals of SETDB1

SETDB1 is a histone H3-lysine 9-specific methyltransferase that fulfills epigenetic functions inside the nucleus; however, when overexpressed, SETDB1 majorily localizes in the cytoplasm. SETDB1 has a single nuclear-localization-signal (NLS) motif and two successive nuclear-export-signal (NES1 and NE...

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Detalles Bibliográficos
Autores principales: Eom, Jaemin, Jeon, Kyuheum, Park, Jung Sun, Kang, Yong-Kook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807615/
https://www.ncbi.nlm.nih.gov/pubmed/36605719
http://dx.doi.org/10.3389/fcell.2022.1069765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807615/
https://www.ncbi.nlm.nih.gov/pubmed/36605719
http://dx.doi.org/10.3389/fcell.2022.1069765

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