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Modified method for differentiation of myeloid-derived suppressor cells in vitro enhances immunosuppressive ability via glutathione metabolism

Myeloid-derived suppressor cells (MDSCs), which accumulate in tumor bearers, are known to suppress anti-tumor immunity and thus promote tumor progression. MDSCs are considered a major cause of resistance against immune checkpoint inhibitors in patients with cancer. Therefore, MDSCs are potential tar...

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Detalles Bibliográficos
Autores principales: Zhou, Haoyang, Xie, Zhiqi, Morikawa, Naosuke, Sakurai, Fuminori, Mizuguchi, Hiroyuki, Okuzaki, Daisuke, Okada, Naoki, Tachibana, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807831/
https://www.ncbi.nlm.nih.gov/pubmed/36605123
http://dx.doi.org/10.1016/j.bbrep.2022.101416