Tyrosinase inhibitory mechanism and anti-browning properties of novel kojic acid derivatives bearing aromatic aldehyde moiety

Kojic acid-aromatic aldehydes 6a-6m were synthesized and screened for their anti-tyrosinase activities. These compounds showed potently anti-tyrosinase activity with IC(50) values in the range of 5.32 ± 0.23 to 77.89 ± 3.36 μM compared with kojic acid (IC(50) = 48.05 ± 3.28 μM). Thereinto, compound...

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Detalles Bibliográficos
Autores principales: Peng, Zhiyun, Wang, Guangcheng, He, Yan, Wang, Jing Jing, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807860/
https://www.ncbi.nlm.nih.gov/pubmed/36605465
http://dx.doi.org/10.1016/j.crfs.2022.100421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807860/
https://www.ncbi.nlm.nih.gov/pubmed/36605465
http://dx.doi.org/10.1016/j.crfs.2022.100421

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