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Obeticholic acid and 5β-cholanic acid 3 exhibit anti-tumor effects on liver cancer through CXCL16/CXCR6 pathway

Hepatocellular carcinoma (HCC) is the most common type of liver malignancy with a high incidence and mortality rate. Previous in vitro and in vivo studies have confirmed that liver sinusoidal endothelial cells (LSEC) secrete CXCL16, which acts as a messenger to increase the hepatic accumulation of C...

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Detalles Bibliográficos
Autores principales: Gou, Haoxian, Liu, Shenglu, Liu, Linxin, Luo, Ming, Qin, Shu, He, Kai, Yang, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807878/
https://www.ncbi.nlm.nih.gov/pubmed/36605219
http://dx.doi.org/10.3389/fimmu.2022.1095915